Article
Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry.
Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2017
Thomas Graham D, Hamers Anouk A J, Nakao Catherine, Marcovecchio Paola, Taylor Angela M, McSkimming Chantel, Nguyen Anh Tram, McNamara Coleen A, Hedrick Catherine C
Abstract excerpt
OBJECTIVE: Human monocyte subsets are defined as classical (CD14++CD16-), intermediate (CD14++CD16+), and nonclassical (CD14+CD16+). Alterations in monocyte subset frequencies are associated with clinical outcomes, including cardiovascular disease, in which circulating intermediate monocytes independently predict cardiovascular events. However, delineating mechanisms of monocyte function is hampered by...
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