Article
Thrombotic Thrombocytopenic Purpura Associated With Pegylated Interferon Alfa-2a Use in a Patient With Polycythemia Vera.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Jun 2017
Gangaraju Radhika, Kim Soo J, Dong Jing-Fei, Swierczek Sabina, Prchal Josef T
Abstract excerpt
Pegylated interferon alfa-2a (pegIFNa) is being increasingly used for treatment of myeloproliferative neoplasms; however, its side effects, including autoimmune complications, are not unusual. We report on a 47-year-old woman with polycythemia vera (PV) treated with pegIFNa and in complete hematologic remission who developed thrombotic thrombocytopenic purpura (TTP). To our knowledge, thrombotic microangiopathy...
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