Article
[Interferon-alpha-2b induces molecular responses of patients with polycythemia vera and its post-polycythemic myelofibrosis].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2011
Bai Jie, Xue Yang-Ping, Zhang Lei, Li Chun-Hua, Fan Dong-Mei, Li Bin, Xu Shi-Cai, Li Da-Peng, Sun Xiu-Juan, Jiang Bo, Yang Ren-Chi
Abstract excerpt
To evaluate the efficacy and safety of interferon-alpha-2b (IFN-α-2b) in polycythemia vera patients(PV patient) with or without post-polycythemic myelofibrosis (post-PV MF), 30 patients with mutated JAK2V617F were enrolled in this study, from which 29 patients were evaluable. The percentage of mutated JAK2V617F allele (V617F%) was evaluated by real-time polymerase chain reaction (RT-PCR) before and after...
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