Article
Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism.
Scientific reports - 6 Jun 2017
Li Man, Maruthur Nisa M, Loomis Stephanie J, Pietzner Maik, North Kari E, Mei Hao, Morrison Alanna C, Friedrich Nele, Pankow James S, Nauck Matthias, Boerwinkle Eric, Teumer Alexander, Selvin Elizabeth, Köttgen Anna
Abstract excerpt
1,5-anhydroglucitol (1,5-AG) is a biomarker of hyperglycemic excursions associated with diabetic complications. Because of its structural similarity to glucose, genetic studies of 1,5-AG can deliver complementary insights into glucose metabolism. We conducted genome-wide association studies of serum 1,5-AG concentrations in 7,550 European ancestry (EA) and 2,030 African American participants (AA) free of...
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