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Article

Emergence in Italy of a Neisseria meningitidis clone with decreased susceptibility to penicillin.

Antimicrobial agents and chemotherapy - 1 Aug 2004

Stefanelli Paola, Fazio Cecilia, Neri Arianna, Sofia Tonino, Mastrantonio Paola

Abstract excerpt

A rise in invasive diseases due to Neisseria meningitidis C:2b:P1.5 with decreased penicillin susceptibility occurred in Italy during the last 2 years. Real-time PCR identified the Peni phenotype, and the penA sequence revealed the mosaicism of the gene. Molecular analyses assigned the isolates to a single emergent clone of the hypervirulent A4 cluster.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15273126
DOI: 10.1128/AAC.48.8.3103-3106.2004
PMCID: PMC478501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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