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Novel zona pellucida gene variants identified in patients with oocyte anomalies.

Fertility and sterility - 1 Jun 2017

Yang Ping, Luan Xin, Peng Yingqian, Chen Tailai, Su Shizhen, Zhang Changming, Wang Zhao, Cheng Lei, Zhang Xin, Wang Ying, Chen Zi-Jiang, Zhao Han

Abstract excerpt

OBJECTIVE: To detect ZP (zona pellucida) gene (ZP1-ZP4) mutations in patients with oocyte anomalies. DESIGN: Case-control genetic study. SETTING: University-based reproductive medicine center. PATIENT(S): A total of 92 infertile patients with repeated cycles of oocyte maturation arrest (group I, n = 49) or oocyte morphologic defect (group II, n = 43) as well as 373 healthy controls. INTERVENTION(S): Genomic DNA...

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PMID: 28577617
DOI: 10.1016/j.fertnstert.2017.03.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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