Article
Genetic and physiological study of morphologically abnormal human zona pellucida.
European journal of obstetrics, gynecology, and reproductive biology - 1 Nov 2012
Margalit Michal, Paz Gedalia, Yavetz Haim, Yogev Leah, Amit Ami, Hevlin-Schwartz Tamar, Gupta Satish K, Kleiman Sandra E
Abstract excerpt
OBJECTIVE: To investigate genetic, molecular and functional aspects of human zona pellucida (ZP) in oocytes with an abnormal appearance. STUDY DESIGN: The study included three women with unexplained infertility whose oocytes had an abnormal ZP appearance and the mother and fertile sister of one of them. The coding exons and their flanking intron regions of the four ZP genes and the regulatory element for the ZP3...
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