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Article

Novel mutations in ZP1 and ZP2 cause primary infertility due to empty follicle syndrome and abnormal zona pellucida.

Journal of assisted reproduction and genetics - 1 Nov 2020

Luo Geng, Zhu Lixia, Liu Zhenxing, Yang Xue, Xi Qingsong, Li Zhou, Duan Jinliang, Jin Lei, Zhang Xianqin

Abstract excerpt

PURPOSE: Mutations in the zona pellucida glycoprotein genes have been reported to be associated with empty follicle syndrome (EFS) and abnormal zona pellucida (ZP). In this study, we performed genetic analysis in the patients with female infertility due to abnormal zona pellucida and empty follicle syndrome to identify the disease-causing gene mutations in these patients. METHODS: We characterized three patients...

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Source

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Identifiers

PMID: 32829425
DOI: 10.1007/s10815-020-01926-z
PMCID: PMC7642144

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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