Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of insulin resistance in experimental diabetic retinopathy—Genetic and molecular aspects

2 Jun 2017

Abstract excerpt

BACKGROUND: Diabetic retinopathy is characterized by defects in the retinal neurovascular unit. The underlying mechanisms of impairment-including reactive intermediates and growth-factor dependent signalling pathways and their possible interplay are incompletely understood. This study aims to assess the relative role of hyperglycemia and hyperinsulinemia alone or in combination on the gene expression patterning...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments
Share to Retinal Imaging and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28575111
DOI: 10.1371/journal.pone.0178658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of insulin resistance in experimental diabetic retinopathy—Genetic and molecular aspectsPMID 28575111Read ↗

Transcriptomic comparison of the retina in two mouse models of diabetesSemantic proximity Read ↗

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptomeSemantic proximity Read ↗

Differences in junction-associated gene expression changes in three rat models of diabetic retinopathy with similar neurovascular phenotype.Semantic proximity Read ↗

Identification of key genes modules linking diabetic retinopathy and circadian rhythmSemantic proximity Read ↗

Multi-Modal Proteomic Analysis of Retinal Protein Expression Alterations in a Rat Model of Diabetic RetinopathySemantic proximity Read ↗

Bioinformatic analysis of retinal gene function and expression in diabetic ratsSemantic proximity Read ↗

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory responseSemantic proximity Read ↗

Advancing Diabetic Retinopathy Research: Analysis of the Neurovascular Unit in ZebrafishSemantic proximity Read ↗

Altered Retinal MicroRNA Expression Profiles in Early Diabetic Retinopathy: An<i>In Silico</i>AnalysisSemantic proximity Read ↗

The pathogenesis of diabetic retinopathy: old concepts and new questionsSemantic proximity Read ↗

Beyond drug discovery: Exploring the physiological and methodological dimensions of zebrafish in diabetes researchSemantic proximity Read ↗

Combination of blockade of endothelin signalling and compensation of IGF1 expression confers protective effects on degenerating retinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.