Article
Differences in junction-associated gene expression changes in three rat models of diabetic retinopathy with similar neurovascular phenotype.
Neurobiology of disease - 1 Jan 2023
Kolibabka Matthias, Dannehl Marcus, Oezer Kübra, Murillo Katharina, Huang Hongpeng, Riemann Sarah, Hoffmann Sigrid, Gretz Norbert, Schlotterer Andrea, Feng Yuxi, Hammes Hans-Peter
Abstract excerpt
Diabetic retinopathy, also defined as microvascular complication of diabetes mellitus, affects the entire neurovascular unit with specific aberrations in every compartment. Neurodegeneration, glial activation and vasoregression are observed consistently in models of diabetic retinopathy. However, the order and the severity of these aberrations varies in different models, which is also true in patients. In this...
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