Article
A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients.
Investigative ophthalmology & visual science - 1 May 2017
Hamanaka Teruhiko, Kimura Masae, Sakurai Tetsuro, Ishida Nobuo, Yasuda Jun, Nagasaki Masao, Nariai Naoki, Endo Atsushi, Homma Kei, Katsuoka Fumiki, Matsubara Yoichi, Yamamoto Masayuki, Fuse Nobuo
Abstract excerpt
Purpose: This study evaluated specific relationships between pathogenic mechanisms and genetic polymorphisms in primary open-angle glaucoma (POAG). We analyzed the morphologies of trabeculectomy specimens obtained from patients with familial POAG. Methods: We used light microscopy and transmission electron microscopy to examine specimens obtained from 17 eyes of 14 patients with familial POAG. We also conducted...
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