Article
Role of human rhinovirus in triggering human airway epithelial-mesenchymal transition.
Respiratory research - 30 May 2017
Minor Danielle M, Proud David
Abstract excerpt
BACKGROUND: Structural changes in the airways, collectively referred to as airway remodeling, are a characteristic feature of asthma, and are now known to begin in early life. Human rhinovirus (HRV)-induced wheezing illnesses during early life are a potential inciting stimulus for remodeling. Increased deposition of matrix proteins causes thickening of the lamina reticularis, which is a well-recognized component...
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