Article
Heart failure and endothelial nitric oxide synthase G894T gene polymorphism frequency variations within ancestries.
Nitric oxide : biology and chemistry - 28 Feb 2018
Oliveira Romulo V M, Albuquerque Felipe N, Duque Gustavo S, Freitas Rossana G A, Carvalho Elizeu F, Brandão Andrea A, Silva Dayse A, Mourilhe-Rocha Ricardo, Albuquerque Denilson C
Abstract excerpt
The G894T polymorphism in endothelial nitric oxide synthase enzyme gene plays an important role in heart failure (HF) and its frequency varies among populations. We investigated this association in highly admixed samples in terms of ancestry. The cohort included 210 HF patients and 106 healthy individuals. Self-reported race and NYHA class were analyzed for HF patients. G894T polymorphism was analyzed by...
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