Article
Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration.
Annual review of genomics and human genetics - 1 Jan 2009
Swaroop Anand, Chew Emily Y, Rickman Catherine Bowes, Abecasis Gonçalo R
Abstract excerpt
Aging-associated neurodegenerative diseases significantly influence the quality of life of affected individuals. Genetic approaches, combined with genomic technology, have provided powerful insights into common late-onset diseases, such as age-related macular degeneration (AMD). Here, we discuss current findings on the genetics of AMD to highlight areas of rapid progress and new challenges. We also attempt to...
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