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Article

Variability in coronary artery anatomy affects consistency of cardiac damage after myocardial infarction in mice.

American journal of physiology. Heart and circulatory physiology - 1 Aug 2017

Chen Jiqiu, Ceholski Delaine K, Liang Lifan, Fish Kenneth, Hajjar Roger J

Abstract excerpt

Low reliability and reproducibility in heart failure models are well established. The purpose of the present study is to explore factors that affect model consistency of myocardial infarction (MI) in mice. MI was induced by left coronary artery (LCA) ligation. The coronary artery was casted with resin and visualized with fluorescent imaging ex vivo. LCA characteristics and MI size were analyzed individually in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28550174
DOI: 10.1152/ajpheart.00127.2017
PMCID: PMC5582916

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