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Article

A haplotype block downstream of plasminogen is associated with chronic and aggressive periodontitis.

Journal of clinical periodontology - 1 Oct 2017

Munz Matthias, Chen Hong, Jockel-Schneider Yvonne, Adam Knut, Hoffman Per, Berger Klaus, Kocher Thomas, Meyle Jörg, Eickholz Peter, Doerfer Christof, Laudes Matthias, Uitterlinden André, Lieb Wolfgang, Franke Andre, Schreiber Stefan, Offenbacher Steven, Divaris Kimon, Bruckmann Corinna, Loos Bruno G, Jepsen Søeren, Dommisch Henrik, Schäefer Arne S

Abstract excerpt

AIM: The intronic variant rs4252120 in the plasminogen gene (PLG) is known to be associated with aggressive periodontitis (AgP) and atherosclerosis. Here, we examined the chromosomal region spanning PLG for associations with both chronic periodontitis (CP) and AgP. MATERIALS AND METHODS: The association of PLG candidate rs4252120 was tested in a German case-control sample of 1,419 CP cases using the genotyping...

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Identifiers

PMID: 28548211
DOI: 10.1111/jcpe.12749

Genes

PLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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