Article
The power to detect quantitative trait loci using resequenced, experimentally evolved populations of diploid, sexual organisms.
Molecular biology and evolution - 1 Apr 2014
Baldwin-Brown James G, Long Anthony D, Thornton Kevin R
Abstract excerpt
A novel approach for dissecting complex traits is to experimentally evolve laboratory populations under a controlled environment shift, resequence the resulting populations, and identify single nucleotide polymorphisms (SNPs) and/or genomic regions highly diverged in allele frequency. To better understand the power and localization ability of such an evolve and resequence (E&R) approach, we carried out...
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