Article
Characterizing the roles of changing population size and selection on the evolution of flux control in metabolic pathways.
BMC evolutionary biology - 25 May 2017
Orlenko Alena, Chi Peter B, Liberles David A
Abstract excerpt
BACKGROUND: Understanding the genotype-phenotype map is fundamental to our understanding of genomes. Genes do not function independently, but rather as part of networks or pathways. In the case of metabolic pathways, flux through the pathway is an important next layer of biological organization up from the individual gene or protein. Flux control in metabolic pathways, reflecting the importance of mutation to...
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