Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BMP4 enhances hepatocellular carcinoma proliferation by promoting cell cycle progression via ID2/CDKN1B signaling

23 May 2017

Abstract excerpt

Bone morphogenetic protein-4 (BMP4) plays a crucial role in carcinogenesis, but the effects and signaling mechanisms of BMP4 in hepatocellular carcinoma (HCC) are not clearly clarified. The present study aimed to identify the roles of BMP4 in the proliferation of human HCC. In this study, BMP4 expression and its correlation with clinicopathological characteristics and the survival of HCC patients were analyzed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Pancreatic and Hepatic Oncology Research
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28543546
DOI: 10.1002/mc.22681

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BMP4 enhances hepatocellular carcinoma proliferation by promoting cell cycle progression via ID2/CDKN1B signalingPMID 28543546Read ↗

BMP4 promotes the metastasis of gastric cancer by inducing epithelial–mesenchymal transition via ID1Semantic proximity Read ↗

CYB5D2 inhibits the malignant progression of hepatocellular carcinoma by inhibiting TGF-β expression and epithelial-mesenchymal transitionSemantic proximity Read ↗

BMP4 reprograms glucose metabolism in hepatocellular carcinoma (HCC) cells by upregulating glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axisSemantic proximity Read ↗

SMAD4 exerts a tumor-promoting role in hepatocellular carcinomaSemantic proximity Read ↗

IGFBP2 upregulates ZEB1 expression and promotes hepatocellular carcinoma progression through NF-κB signaling pathwaySemantic proximity Read ↗

BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinomaSemantic proximity Read ↗

BMP10 suppresses hepatocellular carcinoma progression via PTPRS–STAT3 axisSemantic proximity Read ↗

Bone morphogenetic protein 4-a fascinating regulator of cancer cell behavior.Semantic proximity Read ↗

Identification of a Putative Autocrine Bone Morphogenetic Protein-Signaling Pathway in Human Ovarian Surface Epithelium and Ovarian Cancer CellsSemantic proximity Read ↗

BMP2 as a promising anticancer approach: functions and molecular mechanismsSemantic proximity Read ↗

Id2 and Id3 Define the Potency of Cell Proliferation and Differentiation Responses to Transforming Growth Factor β and Bone Morphogenetic ProteinSemantic proximity Read ↗

Autocrine BMP4 Signaling Enhances Tumor Aggressiveness via Promoting Wnt/β-Catenin Signaling in IDH1-mutant GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.