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Article

Cross-modulation of homeostatic responses to temperature, oxygen and carbon dioxide in C. elegans.

PLoS genetics - 1 Jan 2013

Kodama-Namba Eiji, Fenk Lorenz A, Bretscher Andrew J, Gross Einav, Busch K Emanuel, de Bono Mario

Abstract excerpt

Different interoceptive systems must be integrated to ensure that multiple homeostatic insults evoke appropriate behavioral and physiological responses. Little is known about how this is achieved. Using C. elegans, we dissect cross-modulation between systems that monitor temperature, O₂ and CO₂. CO₂ is less aversive to animals acclimated to 15°C than those grown at 22°C. This difference requires the AFD neurons,...

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Identifiers

PMID: 24385919
DOI: 10.1371/journal.pgen.1004011
PMCID: PMC3868554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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