Article
Co-inheritance of glucose-6-phosphate dehydrogenase deficiency mutations and hemoglobin E in a Kachin population in a malaria-endemic region of Southeast Asia.
PloS one - 1 Jan 2017
Deng Zeshuai, Yang Fang, Bai Yao, He Lijun, Li Qing, Wu Yanrui, Luo Lan, Li Hong, Ma Limei, Yang Zhaoqing, He Yongshu, Cui Liwang
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) deficiency and hemoglobin E (HbE, β26 Glu-Lys) are two common red cell disorders in Southeast Asia. G6PD deficiency produces hemolytic anemia, which can be triggered by certain drugs or infections. HbE is asymptomatic or is manifested as microcytic, minimally hemolytic anemia. The association between G6PD deficiency and HbE is little understood. This study aimed to...
Topics
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- China
- Comorbidity
- Endemic Diseases
- Female
- Genotype
- Glucosephosphate Dehydrogenase
- Glucosephosphate Dehydrogenase Deficiency
- Hemoglobin E