Article
PvGAMA reticulocyte binding activity: predicting conserved functional regions by natural selection analysis.
Parasites & vectors - 19 May 2017
Baquero Luis A, Moreno-Pérez Darwin A, Garzón-Ospina Diego, Forero-Rodríguez Johanna, Ortiz-Suárez Heidy D, Patarroyo Manuel A
Abstract excerpt
BACKGROUND: Adhesin proteins are used by Plasmodium parasites to bind and invade target cells. Hence, characterising molecules that participate in reticulocyte interaction is key to understanding the molecular basis of Plasmodium vivax invasion. This study focused on predicting functionally restricted regions of the P. vivax GPI-anchored micronemal antigen (PvGAMA) and characterising their reticulocyte binding...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
