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Article

Association Analysis of Nonsyndromic Congenital Heart Disease and Tag Single Nucleotide Polymorphisms of TBX20 and Genes in the Ras-MAPK Pathway.

Genetic testing and molecular biomarkers - 1 Jul 2017

Luo Zhiling, Shen Yan, Chen Wei, Ma Xuejuan, Liu Liping, Huang Xiaoqin, Yang Zhaoqing, Sun Hao

Abstract excerpt

AIMS: The present study was performed to determine whether there are variants in TBX20 and genes of the Ras-MAPK pathway associated with nonsyndromic congenital heart disease (ns-CHD). MATERIALS AND METHODS: A total of 223 ns-CHD patients and 273 healthy controls from China were selected as study subjects to perform an association analysis using 22 tag single-nucleotide polymorphisms (tag SNPs) located either in...

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Source

Identifiers

PMID: 28525297
DOI: 10.1089/gtmb.2016.0369

Genes

TBX20
BRAF
RAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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