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Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis

18 May 2017

Abstract excerpt

Cystatin SN (CST1) belongs to the type 2 cystatin (CST) superfamily, which restricts the proteolytic activities of cysteine proteases. CST1 has been recently considered to be involved in the development of several human cancers. However, the prognostic significance and function of CST1 in breast cancer remains unknown. In the current study, we found that CST1 was generally upregulated in breast cancer at both...

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PMID: 28523467
DOI: 10.1007/s00109-017-1537-1

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