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Article

Network Meta-Analysis on the Effects of DNA Damage Response-Related Gene Mutations on Overall Survival of Breast Cancer Based on TCGA Database.

Journal of cellular biochemistry - 1 Dec 2017

Liu Chang, Chang Hong, Li Xiao-Han, Qi Ya-Fei, Wang Jin-Ou, Zhang Ying, Yang Xiang-Hong

Abstract excerpt

The study was conducted for comparing the effects of 12 DNA damage response gene mutations (CHEK1, CHEK2, RAD51, BRCA1, BRCA2, MLH1, MSH2, ATM, ATR, MDC1, PARP1, and FANCF) on the overall survival (OS) of breast cancer (BC) patients. We searched the Cancer Genome Atlas (TCGA) database from inception to September 2016. Studies that investigated the association between 12 DNA damage responses related genes and BC...

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Source

Identifiers

PMID: 28513990
DOI: 10.1002/jcb.26140

Genes

MDC1
ATM
ATR
BRCA1
BRCA2
CHEK1
CHEK2
FANCF
MLH1
MSH2
PARP1
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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