Article
Association study of genetic variation in the autophagy lysosome pathway genes and risk of eight kinds of cancers.
International journal of cancer - 1 Jul 2018
Tan Juan, Fu Linna, Chen Haoyan, Guan Jian, Chen Yingxuan, Fang Jingyuan
Abstract excerpt
The autophagy lysosome pathway is essential to maintain cell viability and homeostasis in response to many stressful environments, which is reported to play a vital role in cancer development and therapy. However, the association of genetic alterations of this pathway with risk of cancer remains unclear. Based on genome-wide association study data of eight kinds of cancers, we used an adaptive rank truncated...
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