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Article

Effect of chitosan and coagulation factors on the wound repair phenotype of bioengineered blood clots.

International journal of biological macromolecules - 1 Nov 2017

Hoemann Caroline D, Marchand Catherine, Rivard Georges-Etienne, El-Gabalawy Hani, Poubelle Patrice E

Abstract excerpt

Controlling the blood clot phenotype in a surgically prepared wound is an evolving concept in scaffold-guided tissue engineering. Here, we investigated the effect of added chitosan (80% or 95% Degree of Deacetylation, DDA) or coagulation factors (recombinant human Factor VIIa, Tissue Factor, thrombin) on inflammatory factors released by blood clots. We tested the hypothesis that 80% DDA chitosan specifically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28512053
DOI: 10.1016/j.ijbiomac.2017.04.114

Genes

CXCL8
CCL3
CCL4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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