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Article

Next generation sequencing is informing phenotype: a TP53 example.

Familial cancer - 1 Jan 2018

O'Shea R, Clarke R, Berkley E, Giffney C, Farrell M, O'Donovan E, Gallagher D J

Abstract excerpt

The increased availability of next generation sequencing (NGS) and multi gene panel testing has resulted in more frequent TP53 testing of families that do not meet classic testing criteria. We investigated testing criteria, family history and result outcome in a cohort of Irish probands undergoing TP53 full sequencing. All TP53 test requests processed through the national genetic testing laboratory between 2012...

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Identifiers

PMID: 28509937
DOI: 10.1007/s10689-017-0002-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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