Article
New Prodigiosin Derivatives Obtained by Mutasynthesis in Pseudomonas putida.
ACS synthetic biology - 15 Sept 2017
Klein Andreas S, Domröse Andreas, Bongen Patrick, Brass Hannah U C, Classen Thomas, Loeschcke Anita, Drepper Thomas, Laraia Luca, Sievers Sonja, Jaeger Karl-Erich, Pietruszka Jörg
Abstract excerpt
The deeply red-colored natural compound prodigiosin is a representative of the prodiginine alkaloid family, which possesses bioactivities as antimicrobial, antitumor, and antimalarial agents. Various bacteria including the opportunistic human pathogen Serratia marcescens and different members of the Streptomycetaceae and Pseudoalteromonadaceae produce prodiginines. In addition, these microbes generally accumulate...
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