Article
Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging.
The Journal of investigative dermatology - 1 Sept 2017
Law Matthew H, Medland Sarah E, Zhu Gu, Yazar Seyhan, Viñuela Ana, Wallace Leanne, Shekar Sri Niranjan, Duffy David L, Bataille Veronique, Glass Dan, Spector Tim D, Wood Diane, Gordon Scott D, Barbour Julie M, Henders Anjali K, Hewitt Alex W, Montgomery Grant W, Sturm Richard A, Mackey David A, Green Adèle C, Martin Nicholas G, MacGregor Stuart
Abstract excerpt
Loss of fine skin patterning is a sign of both aging and photoaging. Studies investigating the genetic contribution to skin patterning offer an opportunity to better understand a trait that influences both physical appearance and risk of keratinocyte skin cancer. We undertook a meta-analysis of genome-wide association studies of a measure of skin pattern (microtopography score) damage in 1,671 twin pairs and...
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