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Article

Different Polyubiquitinated Bodies in Human Dendritic Cells: IL-4 Causes PaCS During Differentiation while LPS or IFNα Induces DALIS During Maturation.

Scientific reports - 12 May 2017

Montagna Daniela, Sommi Patrizia, Necchi Vittorio, Vitali Agostina, Montini Enrica, Turin Ilaria, Ferraro Daniela, Ricci Vittorio, Solcia Enrico

Abstract excerpt

Two types of polyubiquitin-reactive cytoplasmic bodies, particulate cytoplasmic structures (PaCS) and dendritic cell (DC) aggresome-like induced structures (DALIS), were analyzed by electron microscopy, immunocytochemistry, immunoblotting, and flow cytometry in DC obtained from human blood monocytes incubated with GM-CSF plus IL-4 (IL4-DC), GM-CSF plus IFNα (IFN-DC), or GM-CSF alone (GM-DC), with or without LPS...

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Identifiers

PMID: 28500302
DOI: 10.1038/s41598-017-02090-8
PMCID: PMC5431999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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