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Article

Metformin, Lifestyle Intervention, and Cognition in the Diabetes Prevention Program Outcomes Study.

Diabetes care - 1 Jul 2017

Luchsinger José A, Ma Yong, Christophi Costas A, Florez Hermes, Golden Sherita H, Hazuda Helen, Crandall Jill, Venditti Elizabeth, Watson Karol, Jeffries Susan, Manly Jennifer J, Pi-Sunyer F Xavier

Abstract excerpt

OBJECTIVE: We examined the association of the Diabetes Prevention Program (DPP) intervention arms (lifestyle intervention, metformin, and placebo) with cognition in the Diabetes Prevention Program Outcomes Study (DPPOS). We also examined metformin use, incident type 2 diabetes, and glycemia as exposures. RESEARCH DESIGN AND METHODS: The DPP lasted 2.8 years, followed by a 13-month bridge to DPPOS. Cognition was...

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Identifiers

PMID: 28500216
DOI: 10.2337/dc16-2376
PMCID: PMC5481986

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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