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Article

Polymorphism in ABC transporter genes of Dirofilaria immitis.

International journal for parasitology. Drugs and drug resistance - 1 Aug 2017

Mani Thangadurai, Bourguinat Catherine, Prichard Roger K

Abstract excerpt

Dirofilaria immitis, a filarial nematode, causes dirofilariasis in dogs, cats and occasionally in humans. Prevention of the disease has been mainly by monthly use of the macrocyclic lactone (ML) endectocides during the mosquito transmission season. Recently, ML resistance has been confirmed in D. immitis and therefore, there is a need to find new classes of anthelmintics. One of the mechanisms associated with ML...

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Identifiers

PMID: 28494332
DOI: 10.1016/j.ijpddr.2017.04.004
PMCID: PMC5421822

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