Article
Glioma Grading and Determination of IDH Mutation Status and ATRX loss by DCE and ASL Perfusion.
Clinical neuroradiology - 1 Sept 2018
Brendle Cornelia, Hempel Johann-Martin, Schittenhelm Jens, Skardelly Marco, Tabatabai Ghazaleh, Bender Benjamin, Ernemann Ulrike, Klose Uwe
Abstract excerpt
PURPOSE: To evaluate arterial spin labeling (ASL) perfusion and dynamic contrast-enhanced (DCE) perfusion in glioma grading according to the previous WHO classification of 2007, as well as concerning isocitrate dehydrogenase (IDH) mutation status and ATRX expression as required by the new WHO 2016 brain tumor classification. METHODS: The mean values of Ktrans, Kep, Ve, and Vp by DCE perfusion, and cerebral blood...
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