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Article

Elevated Levels of Selenium Species in Cerebrospinal Fluid of Amyotrophic Lateral Sclerosis Patients with Disease-Associated Gene Mutations.

Neuro-degenerative diseases - 1 Jan 2017

Mandrioli Jessica, Michalke Bernhard, Solovyev Nikolay, Grill Peter, Violi Federica, Lunetta Christian, Conte Amelia, Sansone Valeria Ada, Sabatelli Mario, Vinceti Marco

Abstract excerpt

BACKGROUND: Although an increasing role of genetic susceptibility has been recognized, the role of environmental risk factors in amyotrophic lateral sclerosis (ALS) etiology is largely uncertain; among neurotoxic chemicals, epidemiological and biological plausibility has been provided for pesticides, the heavy metal lead, the metalloid selenium, and other persistent organic pollutants. Selenium involvement in ALS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28478440
DOI: 10.1159/000460253

Genes

ATXN2
FUS
SOD1
TARDBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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