Article
Sak and Sak4 recombinases are required for bacteriophage replication in Staphylococcus aureus.
Nucleic acids research - 20 Jun 2017
Neamah Maan M, Mir-Sanchis Ignacio, López-Sanz María, Acosta Sonia, Baquedano Ignacio, Haag Andreas F, Marina Alberto, Ayora Silvia, Penadés José R
Abstract excerpt
DNA-single strand annealing proteins (SSAPs) are recombinases frequently encoded in the genome of many bacteriophages. As SSAPs can promote homologous recombination among DNA substrates with an important degree of divergence, these enzymes are involved both in DNA repair and in the generation of phage mosaicisms. Here, analysing Sak and Sak4 as representatives of two different families of SSAPs present in phages...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.