Article
SaPI mutations affecting replication and transfer and enabling autonomous replication in the absence of helper phage.
Molecular microbiology - 1 Feb 2008
Ubeda Carles, Maiques Elisa, Barry Peter, Matthews Avery, Tormo María Angeles, Lasa Iñigo, Novick Richard P, Penadés José R
Abstract excerpt
The SaPIs are chromosomal islands in staphylococci and other Gram-positive bacteria that carry genes for superantigens, virulence factors, resistance and certain metabolic functions. They have intimate relationships with certain temperate phages involving phage-induced excision, replication and efficient packaging in special small-headed infective phage-like particles, resulting in very high transfer frequencies....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.