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Article

Staphylococcal pathogenicity island DNA packaging system involving cos-site packaging and phage-encoded HNH endonucleases.

Proceedings of the National Academy of Sciences of the United States of America - 22 Apr 2014

Quiles-Puchalt Nuria, Carpena Nuria, Alonso Juan C, Novick Richard P, Marina Alberto, Penadés José R

Abstract excerpt

Staphylococcal pathogenicity islands (SaPIs) are the prototypical members of a widespread family of chromosomally located mobile genetic elements that contribute substantially to intra- and interspecies gene transfer, host adaptation, and virulence. The key feature of their mobility is the induction of SaPI excision and replication by certain helper phages and their efficient encapsidation into phage-like...

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Identifiers

PMID: 24711396
DOI: 10.1073/pnas.1320538111
PMCID: PMC4000808

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