Article
Investigation of ospC Expression Variation among Borrelia burgdorferi Strains.
Frontiers in cellular and infection microbiology - 1 Jan 2017
Xiang Xuwu, Yang Youyun, Du Jimei, Lin Tianyu, Chen Tong, Yang X Frank, Lou Yongliang
Abstract excerpt
Outer surface protein C (OspC) is the most studied major virulence factor of Borrelia burgdorferi, the causative agent of Lyme disease. The level of OspC varies dramatically among B. burgdorferi strains when cultured in vitro, but little is known about what causes such variation. It has been proposed that the difference in endogenous plasmid contents among strains contribute to variation in OspC phenotype, as B....
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