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Article

Sex Hormones and Sex Chromosomes Cause Sex Differences in the Development of Cardiovascular Diseases.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2017

Arnold Arthur P, Cassis Lisa A, Eghbali Mansoureh, Reue Karen, Sandberg Kathryn

Abstract excerpt

This review summarizes recent evidence concerning hormonal and sex chromosome effects in obesity, atherosclerosis, aneurysms, ischemia/reperfusion injury, and hypertension. Cardiovascular diseases occur and progress differently in the 2 sexes, because biological factors differing between the sexes have sex-specific protective and harmful effects. By comparing the 2 sexes directly, and breaking down sex into its...

Topics

Animals
Cardiovascular Diseases
Disease Models, Animal
Female
Genetic Predisposition to Disease
Gonadal Steroid Hormones
Health Status Disparities
Humans
Male
Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Protective Factors

Risk Factors

Sex Chromosomes

Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 28279969
DOI: 10.1161/ATVBAHA.116.307301
PMCID: PMC5437981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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