Article
Copy number variation of FCGR genes in etiopathogenesis of sarcoidosis.
PloS one - 1 Jan 2017
Typiak Marlena, Rębała Krzysztof, Haraś Agnieszka, Skotarczak Monika, Słomiński Jan Marek, Dubaniewicz Anna
Abstract excerpt
We have previously revealed that, in contrast to polymorphism of FCGR2B and FCGR3B, polymorphism of FCGR2A, FCGR2C and FCGR3A genes, encoding receptors for Fc fragment of immunoglobulin G (Fcγ receptors), play a role in increased level of circulating immune complexes with occurrence of Mycobacterium tuberculosis heat shock proteins in patients with sarcoidosis. However, this immunocomplexemia might also be caused...
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