Article
Transgenerational non-genomic transmission of acquired nervous system Phenotypes: Narrative review and epigenetic insights.
Neurochemistry international - 1 Dec 2025
Abou Merhi Anas, Sivan Vivek, Koueik Joyce, Walsh Alexandra, Papale Ligia A, Alisch Reid S, Hogan Kirk, Iskandar Bermans J
Abstract excerpt
Transgenerational epigenetic inheritance (TEI) refers to the transmission of phenotypic traits across multiple generations independent of changes in DNA sequence that are mediated by epigenetic mechanisms, including DNA methylation, histone modifications, chromatin morphology, and non-coding RNAs. This review focuses on manuscripts that report epigenetic mechanisms in the transgenerational inheritance of nervous...
Read the complete abstract on PubMedTopics
- Animals
- Epigenesis, Genetic
- Humans
- Phenotype
- DNA Methylation
- Nervous System