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Article

Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor.

Antimicrobial agents and chemotherapy - 1 Jul 2017

Wang Yaxin, Cao Lin, Zhai Yangyang, Yin Zheng, Sun Yuna, Shang Luqing

Abstract excerpt

Hand-foot-and-mouth disease (HFMD), caused by enterovirus, is a threat to public health worldwide. To date, enterovirus 71 (EV71) has been one of the major causative agents of HFMD in the Pacific-Asia region, and outbreaks with EV71 cause millions of infections. However, no drug is currently available for clinical therapeutics. In our previous works, we developed a set of protease inhibitors (PIs) targeting the...

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Identifiers

PMID: 28461310
DOI: 10.1128/AAC.00298-17
PMCID: PMC5487676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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