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Article

Endometrial cancer gene panels: clinical diagnostic vs research germline DNA testing.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2017

Spurdle Amanda B, Bowman Michael A, Shamsani Jannah, Kirk Judy

Abstract excerpt

Endometrial cancer is the most common gynecological cancer, but is nevertheless uncommon enough to have value as a signature cancer for some hereditary cancer syndromes. Commercial multigene testing panels include up to 13 different genes annotated for germline DNA testing of patients with endometrial cancer. Many other genes have been reported as relevant to familial endometrial cancer from directed genome-wide...

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Identifiers

PMID: 28452373
DOI: 10.1038/modpathol.2017.20

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