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Article

Identification of novel genetic variants in the mutational hotspot region 14 kb upstream of the LCT gene in a Mexican population.

Scandinavian journal of clinical and laboratory investigation - 1 Sept 2017

Valencia Liliana, Randazzo Andrés, Engfeldt Peter, Olsson Lovisa A, Chávez Adolfo, Buckland Robert J, Nilsson Torbjörn K, Almon Ricardo

Abstract excerpt

Several polymorphic loci linked to lactase persistence (LP) have been described, all located in a small mutational hotspot region far upstream (∼14 kb) of the lactase (LCT) gene. One is typically found in Europeans, LCT -13910C > T, several others are found in East Africans and Arabs, e.g. LCT -13907C > G and LCT -13915T > G. The possibility of similar loci, specific to populations in South and Central America,...

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Identifiers

PMID: 28452238
DOI: 10.1080/00365513.2017.1318445

Genes

LCT

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