Article
Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population.
Annals of human biology - 1 Sept 2022
Németh Stefan, Kriegshäuser Gernot, Hovhannesyan Kristine, Hayrapetyan Hasmik, Oberkanins Christian, Sarkisian Tamara
Abstract excerpt
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase persistence variants in a regulatory region upstream of the LCT gene. Here, we genotyped 202 Armenian subjects for LCT-13910T, a lactase persistence variant...
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