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Article

Identification of a variant associated with adult-type hypolactasia.

Nature genetics - 1 Feb 2002

Enattah Nabil Sabri, Sahi Timo, Savilahti Erkki, Terwilliger Joseph D, Peltonen Leena, Järvelä Irma

Abstract excerpt

Adult-type hypolactasia, also known as lactase non-persistence (lactose intolerance), is a common autosomal recessive condition resulting from the physiological decline in activity of the lactase-phlorizin hydrolase (LPH) in intestinal cells after weaning. LPH hydrolyzes lactose into glucose and galactose. Sequence analyses of the coding and promoter regions of LCT, the gene encoding LPH, has revealed no DNA...

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Source

Identifiers

PMID: 11788828
DOI: 10.1038/ng826

Genes

LCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a variant associated with adult-type hypolactasia.PMID 11788828Read ↗

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Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia.Semantic proximity Read ↗

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