Article
RETINOBLASTOMA RELATED1 mediates germline entry in Arabidopsis.
Science (New York, N.Y.) - 28 Apr 2017
Zhao Xin'Ai, Bramsiepe Jonathan, Van Durme Matthias, Komaki Shinichiro, Prusicki Maria Ada, Maruyama Daisuke, Forner Joachim, Medzihradszky Anna, Wijnker Erik, Harashima Hirofumi, Lu You, Schmidt Anja, Guthörl Daniela, Logroño Rosa Sahún, Guan Yonsheng, Pochon Gaetan, Grossniklaus Ueli, Laux Thomas, Higashiyama Tetsuya, Lohmann Jan U, Nowack Moritz K, Schnittger Arp
Abstract excerpt
To produce seeds, flowering plants need to specify somatic cells to undergo meiosis. Here, we reveal a regulatory cascade that controls the entry into meiosis starting with a group of redundantly acting cyclin-dependent kinase (CDK) inhibitors of the KIP-RELATED PROTEIN (KRP) class. KRPs function by restricting CDKA;1-dependent inactivation of the Arabidopsis Retinoblastoma homolog RBR1. In rbr1 and krp triple...
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