Article
Downregulation of multiple CDK inhibitor ICK/KRP genes upregulates the E2F pathway and increases cell proliferation, and organ and seed sizes in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Aug 2013
Cheng Yan, Cao Ling, Wang Sheng, Li Yongpeng, Shi Xianzong, Liu Han, Li Lixia, Zhang Zhengli, Fowke Larry C, Wang Hong, Zhou Yongming
Abstract excerpt
The ICK/KRP cyclin-dependent kinase (CDK) inhibitors are important plant cell cycle factors sharing only limited similarity with the metazoan CIP/KIP family of CDK inhibitors. Little is known about the specific functions of different ICK/KRP genes in planta. In this study, we created double and multiple mutants from five single Arabidopsis ICK/KRP T-DNA mutants, and used a set of 20 lines for the functional...
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