Article
FLO1 is a variable green beard gene that drives biofilm-like cooperation in budding yeast.
Cell - 14 Nov 2008
Smukalla Scott, Caldara Marina, Pochet Nathalie, Beauvais Anne, Guadagnini Stephanie, Yan Chen, Vinces Marcelo D, Jansen An, Prevost Marie Christine, Latgé Jean-Paul, Fink Gerald R, Foster Kevin R, Verstrepen Kevin J
Abstract excerpt
The budding yeast, Saccharomyces cerevisiae, has emerged as an archetype of eukaryotic cell biology. Here we show that S. cerevisiae is also a model for the evolution of cooperative behavior by revisiting flocculation, a self-adherence phenotype lacking in most laboratory strains. Expression of the gene FLO1 in the laboratory strain S288C restores flocculation, an altered physiological state, reminiscent of...
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